铜稳态:生命活动的关键调控者及其在疾病中的潜在角色(柠檬酸铜Copper Citrate、氨基酸螯合铜Copper Amino Acid Chelate) 。说出用时:2024-10-19 13:28 铜稳态是近2年热点话题之一 ,最近研究发现依赖铜稳态机制的铜死亡在肿瘤、肝病、神经功能疾病中发挥巨大作用 。铜是人体必需微量元素之一 ,全身含量约为 100mg 。铜在生命活动中发挥着关键催化辅因子的作用 ,包括线粒体呼吸、抗氧化和蛋白质合成等 。值得注意的是 ,细胞内铜浓度一般保持在相对稳定的范围内 ,浓度上升会产生细胞毒性 ,甚至导致细胞死亡 。铜的吸收、分布和清除受到严格调节 ,因此铜稳态平衡的维持对生命活动具有重要意义 ,而铜稳态涉及铜代谢和铜死亡两部分 。维持铜稳态对机体具有重要作用 ,铜失衡会导致氧化应激、氧化应激、自噬、蛋白失活、线粒体功能损伤等一系列反应 ,甚至诱发铜死亡 ,导致细胞发生程序性死亡 。
铜稳态:生命活动的关键调控者及其在疾病中的潜在角色(柠檬酸铜Copper Citrate、氨基酸螯合铜Copper Amino Acid Chelate) 。
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抗坏血酸镁Magnesium Ascorbate 、抗坏血酸锌Magnesium Ascorbate、牛磺酸镁Magnesium Taurate、氨基酸螯合锌Zinc Amino Acids Chelate 、氨基酸螯合镁Magnesium Amino Acids Chelate、乳清酸镁Magnesium Orotate、乳清酸钙Calcium Orotate、琥珀酸钙Calcium Succinate、琥珀酸镁 Magnesium Succinate 、抗坏血酸锂 Lithium Ascorbate.
Copper homeostasis: a key regulator of life activities and its potential role in diseases (copper citrate, copper amino acid chelate).
Copper homeostasis has been one of the hot topics in the past two years. Recent studies have found that copper death, which depends on the copper homeostasis mechanism, plays a huge role in tumors, liver diseases, and neurological diseases. Copper is one of the essential trace elements for the human body, with a total body content of about 100 mg. Copper plays a key catalytic cofactor role in life activities, including mitochondrial respiration, anti-oxidation, and protein synthesis. It is worth noting that the intracellular copper concentration generally remains within a relatively stable range. An increase in concentration will produce cytotoxicity and even lead to cell death. The absorption, distribution, and clearance of copper are strictly regulated, so the maintenance of copper homeostasis is of great significance to life activities, and copper homeostasis involves copper metabolism and copper death. Maintaining copper homeostasis plays an important role in the body. Copper imbalance can lead to a series of reactions such as oxidative stress, oxidative stress, autophagy, protein inactivation, and mitochondrial function damage, and even induce copper death, leading to programmed cell death.
Copper homeostasis: a key regulator of life activities and its potential role in disease (Copper Citrate, Copper Amino Acid Chelate).
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Magnesium Ascorbate, Magnesium Ascorbate, Magnesium Taurate, Zinc Amino Acids Chelate, Magnesium Amino Acids Chelate, Magnesium Orotate, Calcium Orotate, Calcium Succinate, Magnesium Succinate, Lithium Ascorbate.
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